Increlex

Increlex is the brand name for mecasermin, a medication used to treat growth failure in children with severe primary insulin-like growth factor-1 (IGF-1) deficiency. IGF-1 is crucial for growth and development, and children with low levels of this hormone may not grow at the expected rate. Increlex provides synthetic IGF-1 to help stimulate growth in these children.

Key points about Increlex:

• Indication: Primarily used for children with severe primary IGF-1 deficiency.
• Administration: Given as a subcutaneous injection, usually twice daily.
• Dosage: Determined by the patient’s weight and response to treatment.
• Side Effects: May include hypoglycemia (low blood sugar), injection site reactions, and tonsillar hypertrophy (enlargement of the tonsils).
• Contraindications: Not to be used in children with closed epiphyses (growth plates) or active or suspected neoplasia (cancer).
• Precautions: Regular monitoring by a healthcare provider is necessary to adjust dosages and ensure the medication is working effectively without adverse effects.

Always consult with a healthcare provider for personalized medical advice and to understand the potential benefits and risks associated with Increlex.